NRF2 Impact
Polydatin effects on the Nrf2 pathway and why that context matters in oncology
In normal cells, polydatin activates the Nrf2/HO-1/NQO1 antioxidant pathway, providing cytoprotection.
In cancer cells, the effect is more complex and may depend on baseline Nrf2 status, dose, and duration of exposure. This pathway contributes to the compound's favourable safety profile.
See References for Mechanisms of Action Page
This information is for education only. It is not medical advice, diagnosis, or treatment. Please speak with a qualified clinician before making changes to care, medication, or supplement use.
© 2026 Abbey Mitchell. All rights reserved. Please share by URL rather than copying page text.